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Book

Misoprostol

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan.
.
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Book

Misoprostol

Marissa Krugh et al.
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Excerpt

Misoprostol is a synthetic prostaglandin E1 analog approved by the US Food and Drug Administration (FDA) for preventing and treating gastric ulcers induced by nonsteroidal anti-inflammatory drugs (NSAIDs). Misoprostol has 4 primary effects, which include cytoprotection of the gastrointestinal mucosa, uterotonic properties, and the adverse effects of diarrhea, abdominal pain, and nausea. Although not FDA-approved, misoprostol is indicated for the short-term treatment of active duodenal or gastric ulcers caused by factors other than NSAIDs.

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Conflict of interest statement

Disclosure: Marissa Krugh declares no relevant financial relationships with ineligible companies.

Disclosure: Preeti Patel declares no relevant financial relationships with ineligible companies.

Disclosure: Christopher Maani declares no relevant financial relationships with ineligible companies.

References

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