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. 2006 Sep-Oct;8(5):696-704.
doi: 10.1021/cc060066b.

Synthesis of functionalized quinolines via Ugi and Pd-catalyzed intramolecular arylation reactions

Zhibo Ma  1 , Zheng Xiang, Tuoping Luo, Kui Lu, Zhibin Xu, Jiahua Chen, Zhen Yang
Affiliations

Synthesis of functionalized quinolines via Ugi and Pd-catalyzed intramolecular arylation reactions

Zhibo Ma et al. J Comb Chem. 2006 Sep-Oct.

Abstract

Two types of quinoline scaffolds were constructed in a combinatorial format via the Ugi four-component reaction (U-4CR) and Pd-catalyzed intramolecular arylation reaction. The scope of this two-step synthetic sequence was examined from commercially available and synthetically accessible starting materials.

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