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Case Reports
. 2009 Feb;15(1):69-72.

Large-cell neuroendocrine carcinoma of the uterine cervix complicating pregnancy

William W H Li  1 , T N Yau, Carmen W L Leung, W M Pong, May Y M Chan
Affiliations
  • PMID: 19197101
Free article
Case Reports

Large-cell neuroendocrine carcinoma of the uterine cervix complicating pregnancy

William W H Li et al. Hong Kong Med J. 2009 Feb.
Free article

Abstract

Large-cell neuroendocrine cervical carcinoma is a rare and aggressive cancer that tends to spread and recur early despite intensive multimodal treatment. The optimal mode of therapy is still controversial and management during pregnancy is challenging because foetal well-being must also be considered. We report a patient with clinically stage IIB large-cell neuroendocrine cervical carcinoma who presented with a cervical polyp and vaginal bleeding at 18 weeks of pregnancy. The patient received concurrent chemotherapy and radiation after termination of pregnancy and remained in complete remission 21 months after completion of treatment.

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