Regional Brain Activity During Rest and Gastric Water Load in Subtypes of Functional Dyspepsia: A Preliminary Brain Functional Magnetic Resonance Imaging Study

“…In this study, machine learning algorithms were applied to MRI image processing, and the results suggested that it can clearly distinguish the complex brain function differences between healthy volunteers and FES patients, which was consistent with the research results of Kerepesi et al [15], indicating the machine learning algorithm can improve the accuracy of the MRI signal detection results, which had great reference value for monitoring the efficacy of dexmedetomidine combined with MECT treatment. en, fMRI images were included to analyze brain changes in FES patients, and it was found that, before treatment, the ALFF value of the right parietal lobule was higher than the Ctrl group, which was similar to the research results of Suzuki et al [16] and Chen et al [17], indicating that the brain area was active here, while ALFF in the other three places was elevated, but it was not statistically significant; in contrast with before treatment, brain activity in the four brain regions treated by dexmedetomidine combined with MECT was reduced. e four brain regions monitored are located around the frontal lobe-limbic system-parietal nerve anatomical loop, and studies have shown that this loop participates in the pathogenesis of schizophrenia [18], indicating that MECT may have affected the activity intensity of brain neurons in this part, thereby inhibiting psychosis.…”