At 22, Ashley Ringstaff went to a doctor complaining of constant facial numbness and tingling. She was given a prescription for antidepressants and sent on her way. 

Karissa Ostheimer, 34, regularly experienced brief yet terrifying episodes that left her frozen and unable to speak. But only when she had one behind the wheel and crashed her car did doctors consider they could be related to something far more serious than her period. 

"You have to help me, something is very wrong," she begged the third ER doctor she saw. He listened to her and did the right tests, and a much more serious diagnosis emerged.