close
Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Oct;99(10):1357-1358.
doi: 10.1099/jgv.0.001123. Epub 2018 Aug 9.

ICTV Virus Taxonomy Profile: Globuloviridae

David Prangishvili  1 , Mart Krupovic  1 , Ictv Report Consortium
Affiliations

ICTV Virus Taxonomy Profile: Globuloviridae

David Prangishvili et al. J Gen Virol. 2018 Oct.

Abstract

The family Globuloviridae comprises enveloped viruses with linear, double-stranded DNA genomes of about 21-28 kbp. The virions are spherical with a diameter of 70-100 nm. No information is available about genome replication. Globuloviruses infect hyperthermophilic archaea belonging to the genera Pyrobaculum and Thermoproteus, which thrive in extreme geothermal environments. Infection does not cause lysis of host cells and is noncytocidal. The viral genome does not integrate into the host chromosome. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Globuloviridae, which is available at www.ictv.global/report/globuloviridae.

Keywords: Globuloviridae; ICTV Report; Taxonomy.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there are no conflicts of interest.

Figures

Fig. 1.
Fig. 1.
Negative-contrast electron micrographs of virions of Pyrobaculum spherical virus. (Left) Intact virions; arrows indicate spherical protrusions. (Right) Partially disrupted virions extruding helical nucleoprotein core. The bars represent 100 nm (modified from [1]).
Fig. 2.
Fig. 2.
Genome organization of Pyrobaculum spherical virus showing location, sizes and transcriptional direction of putative genes. Genes encoding the three major structural proteins, VP1–3, are shown in black. Paralogous genes are indicated with the same colours. wHTH; gene encoding winged helix-turn-helix domain. Figure modified from [6].
See this image and copyright information in PMC

References

    1. Häring M, Peng X, Brügger K, Rachel R, Stetter KO, et al. Morphology and genome organization of the virus PSV of the hyperthermophilic archaeal genera Pyrobaculum and Thermoproteus: a novel virus family, the Globuloviridae . Virology. 2004;323:233–242. doi: 10.1016/j.virol.2004.03.002. - DOI - PubMed
    1. Ahn DG, Kim SI, Rhee JK, Kim KP, Pan JG, et al. TTSV1, a new virus-like particle isolated from the hyperthermophilic crenarchaeote Thermoproteus tenax . Virology. 2006;351:280–290. doi: 10.1016/j.virol.2006.03.039. - DOI - PubMed
    1. Prangishvili D. Archaeal viruses: living fossils of the ancient virosphere? Ann N Y Acad Sci. 2015;1341:35–40. doi: 10.1111/nyas.12710. - DOI - PubMed
    1. Prangishvili D, Bamford DH, Forterre P, Iranzo J, Koonin EV, et al. The enigmatic archaeal virosphere. Nat Rev Microbiol. 2017;15:724–739. doi: 10.1038/nrmicro.2017.125. - DOI - PubMed
    1. Krupovic M, Cvirkaite-Krupovic V, Iranzo J, Prangishvili D, Koonin EV. Viruses of archaea: structural, functional, environmental and evolutionary genomics. Virus Res. 2018;244:181–193. doi: 10.1016/j.virusres.2017.11.025. - DOI - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources