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Latest comment: 11 years ago1 comment1 person in discussion
Only muscimol and gaboxadol are true GABA-A-Agonists, i.e. bind to the same site of the receptor as GABA itself. The pharmacology of ibotenic acid beside of being a prodrug to muscimol is quite unknown, as far as I know. The "Z-drugs" (es)zopliclone, zolpidem and zaleplon, on the other hand, are not direct agonists, but positive allosteric modulators, just as the benzodiazepines, which allosteric binding site on the GABA-A-receptor they also share. Since this different pharmacological actions lead to huge differences in the subjective effects of those drugs, I really don't think that they should be lumped together. --Diogenes2000 (talk) 17:01, 16 November 2014 (UTC)Reply
Latest comment: 10 years ago1 comment1 person in discussion
The table lists quite a few entactogens as 5ht2aR agonists, which is not true. They should either get their own section or be left in their seperate templateMDMQualone (talk) 05:24, 5 June 2016 (UTC)Reply