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Iditol

From Wikipedia, the free encyclopedia
d-Iditol
Names
IUPAC name
d-Iditol[1]
Systematic IUPAC name
(2R,3S,4S,5R)-Hexane-1,2,3,4,5,6-hexol
Identifiers
3D model (JSmol)
1721905
ChEBI
ChemSpider
ECHA InfoCard 100.125.135 Edit this at Wikidata
EC Number
  • 246-314-3
KEGG
UNII
  • InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5+,6+/m1/s1 checkY
    Key: FBPFZTCFMRRESA-ZXXMMSQZSA-N checkY
  • InChI=1/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5+,6+/m1/s1
    Key: FBPFZTCFMRRESA-ZXXMMSQZBT
  • O[C@@H]([C@H](O)CO)[C@@H](O)[C@H](O)CO
Properties
C6H14O6
Molar mass 182.172 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Iditol is a sugar alcohol[2] which accumulates in galactokinase deficiency.[3]

It can be produced from sorbose by the action of the methanol yeast Candida boidinii at a conversion rate upwards of 90%.[4]

See also

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References

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  1. "2-Carb-19".
  2. "L-Iditol". Human Metabolome Database.
  3. Rubio-Gozalbo, M. Estela; Derks, Britt; Das, Anibh Martin; Meyer, Uta; Möslinger, Dorothea; Couce, M. Luz; Empain, Aurélie; Ficicioglu, Can; Juliá Palacios, Natalia; De Los Santos De Pelegrin, Mariela M.; Rivera, Isabel A.; Scholl-Bürgi, Sabine; Bosch, Annet M.; Cassiman, David; Demirbas, Didem (January 2021). "Galactokinase deficiency: lessons from the GalNet registry". Genetics in Medicine. 23 (1): 202–210. doi:10.1038/s41436-020-00942-9. PMC 7790741. PMID 32807972.
  4. Vongsuvanlert, Vitchuporn; Tani, Yoshiki (1988-01-01). "l-Iditol production from l-sorbose by a methanol yeast, Candida boidinii (Kloeckera sp.) No. 2201". Journal of Fermentation Technology. 66 (5): 517–523. doi:10.1016/0385-6380(88)90084-2.
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